"Healing of critical-size defects is a major challenge to the orthopedic research community," Peroni said. "Large-bone defects must be stabilized and necessitate technologies that induce rapid bone formation in order to replace the missing tissue and allow the individual to return to rapid function. To date, no single material can suffice."
To start the bone regeneration process, the RBC used adult stem cells that produce a protein involved in bone healing and generation. They then incorporated them into a gel, combining the healing properties into something Stice calls "fracture putty."
"The next step is to show that we can rapidly and consistently heal fractures in a large animal," Peroni said, "then to convert it to clinical cases in the UGA [