Insights Search

Monday, October 12, 2026

Topical Vitamin C in DMSO ELIMINATED 86.7% of the World’s Most Common Skin Cancer Within 8 Weeks





You can make this up yourself.  I would even blend the DMSO with olive oil.  Even better, the ascorbic acid powder to make up a useful paste or cream.  The key is high ascorbic acid .

The takehome is that vitimin C will suppress cancers on skin.

This is something you can use.

STUDY: Topical Vitamin C in DMSO ELIMINATED 86.7% of the World’s Most Common Skin Cancer Within 8 Weeks


Nicolas Hulscher, MPH

Epidemiologist & Foundation Administrator at the McCullough Foundation

https://www.linkedin.com/posts/nicolas-hulscher-mph-3683b1274_study-topical-vitamin-c-in-dmso-eliminated-ugcPost-7513686998768005120-ggVg/

A randomized trial reported COMPLETE RESOLUTION of nearly ALL basal cell carcinoma lesions treated with topical 30% ascorbic acid in DMSO.

ANOTHER study found 56% of squamous cell carcinoma in situ lesions were eliminated after 12 weeks of topical vitamin C in DMSO.

Both studies reported excellent tolerability, with NO treatment discontinuations due to adverse effects.

Basal Cell Carcinoma Study: https://lnkd.in/grCbjvvU

Squamous Cell Carcinoma Study: https://lnkd.in/gFAEiFh6




Background Cutaneous squamous cell carcinoma in situ (SCCIS) is a common nonmelanoma skin cancer with rising incidence and substantial treatment costs. While Mohs micrographic surgery remains the standard of care, cost, accessibility, and cosmetic concerns limit its use for some patients. Topical alternatives such as imiquimod and 5-fluorouracil are associated with variable efficacy and frequent adverse effects.


Objective To evaluate the efficacy and tolerability of a 30% ascorbic acid (vitamin C) solution in 95% dimethyl sulfoxide (DMSO) for the treatment of biopsy-confirmed SCCIS.


Methods In this open-label study, 17 patients with 27 histologically confirmed SCCIS lesions applied 30% ascorbic acid in DMSO topically twice daily for 12 weeks. Lesion size and histologic resolution were assessed by repeat biopsy at week 12. Primary outcome was complete resolution of SCCIS; secondary outcomes included lesion size reduction and adverse events.


Results Complete histologic resolution occurred in 15 of 27 lesions (56%), while 44% of lesions showed >85% reduction in size. The mean reduction in lesion area was 71%. Only 2 lesions (7%) failed to respond. Most residual lesions demonstrated actinic atypia without carcinoma and were successfully treated with cryotherapy. No patients discontinued due to adverse effects. Ninety-four percent of participants (16/17) avoided surgical excision.


Conclusions Topical 30% ascorbic acid in DMSO demonstrated promising efficacy and excellent tolerability in the treatment of SCCIS, offering a potential noninvasive alternative to surgery. Larger, controlled trials are warranted.