Saturday, April 6, 2024

A Dynamic Duo–Turmeric and Black Pepper



Anyone adding tumeric to their curry blend can be forgivan for thinking it is mostly a coloring agent.  That too!

folks, I have been making up a curry blend since 1975 and it has been about for over a century before that in the west.  Properly understanding the biochemistry has come about only in the last decade or so.  And it is not just me either.

I personally put both tumeric root, ginger root and pepper into my grapefruit peel pot to produce my extract to produce the base for my nightly elixer. two ounces of bextract.  A shot of gin produces a very nice gin and tonic.  Way better that the commercial tonic water.  It is amazing just how we back engineered ti all .



A Dynamic Duo–Turmeric and Black Pepper

Curcumin, when taken alone, has poor bioavailability—however, when combined with the alkaloid helper, piperine, it becomes a powerhouse for healing.


Turmeric root and black pepper combination enhances bioavailability of cucurmin absorption. (ThamKC/Shutterstock)


4/3/2024Updated:



As a universal “remedy go-to,” turmeric is extremely popular. People talk about it, cook with it, or take supplements filled with the bright yellow powder. Although turmeric has proven to be safe even when ingested in high dosages (12 grams per day), it comes with a little caveat that many might not be aware of.

The rhizome of this native Asian plant contains the polyphenolic compound curcumin, which has a seemingly endless list of beneficial properties. Unfortunately, turmeric displays poor bioavailability—meaning that its salubrious constituents cannot get to their supposed destination easily because regular digestion breaks them down and eliminates them quickly.

Turmeric’s Bioavailability-ProblemA review published in Molecular Pharmaceutics lists “rapid metabolism, and rapid systemic elimination” as two causes, besides poor absorption, that might hinder turmeric reaching its full healing potential in our bodies.

A 2019 review highlights the same pharmacokinetic problems and adds that phase II metabolism in the liver, also called conjugation, severely reduces the oral bioavailability, and speeds up the elimination process.

Don’t Throw the Baby Out With the BathwaterNonetheless, keep your turmeric stockpile in the pantry, as one of the previously mentioned reviews also indicates that even with a lower rate of absorption, curcumin is still a valuable spice with therapeutic efficacy “against various human diseases, including cancer, cardiovascular diseases, diabetes, arthritis, neurological diseases and Crohn’s disease.”

In addition, researchers have been exploring solutions and have found that the alkaloid piperine might do the trick. Piperine is what provides black pepper with its distinct bite and has healthy properties by itself.

Piperine to the RescuePiperine has anti-inflammatory properties that also work to improve fatty liver and reduce insulin resistance. It works against chronic diseases, states a review in Advances in Experimental Medicine and Biology.



That’s not all. In a 2021 analysis in Phytotherapy Research, which considered several in-vitro and in-vivo trials, piperine displayed qualities that fight cancer, such as antitumor, antiproliferative, antiangiogenesis, and antioxidant potentials. The active compound of black pepper also exhibited “antidiabetic, anti-obesity, cardioprotective, antimicrobial, antiaging, and immunomodulatory effects.”

Moreover, black pepper is said to be “hepatoprotective, anti-allergic, anti-inflammatory, and neuroprotective.”


A powerful companion to have.

The Dynamic DuoThe combination of turmeric root and black pepper creates a dynamic duo that counters accelerated elimination and enhances the absorption of turmeric’s medicinal qualities.

In a 2023 comprehensive review, all findings point to the beneficial effects of the curcumin-piperine twosome. People who suffer from diabetes, obesity, or metabolic syndrome can take advantage of the spices’ antioxidant qualities, and those that will improve glycemic indices and lipid profiles.

Furthermore, the paper refers to the duo “reducing oxidative stress and depression in chronic stress and neurological disorders, also improving chronic respiratory diseases, asthma and COVID-19.”

A clinical trial published in Planta Medica compared the absorption rate of curcumin properties in humans and animals. Researchers examined the contrasting assimilation of both sole curcumin and the curcumin/piperine duo.

In the rats, piperine increased the bioavailability of curcumin at a maximum of 154 percent. The assimilation increased even more significantly in humans, where the simultaneous administration of both active substances improved the benefits of turmeric by 2000 percent—without any adverse effects.

Turmeric Supplements and Drug InteractionsWith all these health benefits, some must think “the more the better,” but that is not the case. Mary-Eve Brown, an oncology clinical dietitian and nutritionist at Johns Hopkins Medicine, writes in an article about the dietary facts of turmeric and its drug interactions.

She warns that “turmeric supplements can lessen the effects of [painkillers, such as] indomethacin, aspirin, ibuprofen or acetaminophen” and “increase the risk of bleeding in people taking warfarin,” (a blood thinner).

Ms. Brown also points out that individuals who take the immunosuppressant tacrolimus may experience side effects if ingesting high doses of turmeric. She does go into detail about what those could be but encourages people to rather consume turmeric and black pepper in dietary form, meaning in soups, stews, and other foods and drinks, such as tea.

The likelihood of “overdosing” is much smaller that way, the clinical dietician advises.

If you do opt for a turmeric supplement, however, ensure that black pepper is added to complement the mix.

Practical Application in the KitchenTurmeric has numerous applications in the kitchen. By itself, the yellow spice has an earthy, but mostly bland taste. It’s typically noted for its vigorous color that stains anything it comes into contact with.

Yet, do not be afraid to use the turmeric-pepper duo generously in your cooking. You can add the spices to sautéed or grilled vegetables, in stews and soups, sprinkle them on salads or scrambled eggs, or enhance the flavor of your smoothie.

Since turmeric is one of the main ingredients in curry powder, I like to add the spice mix and some black pepper to my rice water when cooking the grains. This not only gives the usually colorless and bland rice a wonderful hue but provides it with some Middle Eastern flavor and additional health benefits.

A Simple Recipe From My KitchenEspecially for people who like chai lattes or other herbal spiced teas, the following recipe might be a new favorite. Even those who would usually order a syrup-laden and flavored coffee may want to opt for this healthy version of a soothing and warm beverage.

Spiced Turmeric Latte with Black Pepper


Turmeric Latte made with Turmeric, milk, honey or maple syrop and pepper. (Capturastock/Shutterstock)

Ingredients1 cup milk —This can be any type of dairy or nut milk, but you get the most creamy result from using whole milk or light coconut milk. You can also mix two different types of milk and use each 1/2 cup. Try some variations to see what you enjoy most.

2 tsp. freshly grated turmeric root or 1 tsp. dried turmeric powder—for a simpler method you can use 2 turmeric tea bags—To add a little extra “zing,” you can add some freshly ground ginger root or dried ginger to taste. If using fresh ingredients, you want to steep them together with the milk when heating it and strain before drinking.

½ teaspoon honey or maple syrup
Cracked or freshly ground black pepper to taste
A dash of cinnamonInstructions

Combine your favorite variation of milk and bring to near boiling temperature (including any freshly grated ingredients). If not using fresh herbs, pour milk over the tea bags and steep for about four minutes. Strain or remove bags and add honey or maple syrup to taste. Top the finished beverage with the cinnamon powder and the ground pepper. Enjoy!

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