Interesting development. This is unexpected and obviously welcome. We need such a protocol.
Obviously research has taken off and we will see many other applications indicated and confirmed.
all good .
.
Latest Research on CBD Oil Offers New Hope for Healing Leaky Gut Syndrome and Autoimmune Disorders
Contributing writer for Wake Up World
http://wakeup-world.com/2017/02/10/latest-research-on-cbd-oil-offers-new-hope-for-healing-leaky-gut-syndrome-and-autoimmune-disorders/?
For years, leaky gut syndrome (LGS) was
thought to be nothing more than a myth in medical circles — simply a
condition fabricated by ‘fringe’ alternative medicine practitioners to
push their agenda. But times have changed and researchers are beginning
to take a hard look at the role abnormal intestinal permeability plays
in a range of diseases — from autoimmune disorders to food allergies and
even cancer. Characterized by abdominal pain, fatigue, inflammation,
gas, bloating and intolerance to specific edibles, the syndrome can make
life miserable.
Researchers believe LGS is caused when
normally tight junctions of the intestinal lining become compromised and
allow the passage of undigested food particles, toxic waste products,
bacteria and viruses into the bloodstream. Autoimmune disorders can
develop when these foreign particles travel throughout the body and
activate the immune system, which mistakenly attacks the thyroid in case
of Hashimoto’s, joints in rheumatoid arthritis or the intestinal lining
with celiac patients.
Currently, over 80 different autoimmune
diseases have been identified — and the numbers are rapidly rising. It’s
estimated that 23.5 million Americans suffer from an autoimmune
disorder, with 75 percent being female. Incredibly, autoimmune diseases are now among the top 10 leading causes of death in American women under the age of 65.
Emerging research has found a majority
of autoimmune disorders share leaky gut as a common root cause. In fact,
world-renowned pediatric gastroenterologist and research scientist,
Alessio Fasano, MD, believes three factors are always present in all
autoimmune conditions: a genetic susceptibility, antigen exposure, and
increased intestinal permeability.
“Besides celiac disease, several other autoimmune diseases, including type 1 diabetes, multiple sclerosis, and rheumatoid arthritis, are characterized by increased intestinal permeability secondary to non-competent tight junctions that allow the passage of antigens from the intestinal flora, challenging the immune system to produce an immune response that can target any organ or tissue in genetically predisposed individuals,” Fasano notes in the February 2012 issue of Clinical Reviews in Allergy and Immunology. [source]
Contrary to the belief that once an autoimmune disorder is activated it remains ongoing, researchers have discovered that “the
process could be modulated and possibly reversed by interrupting one of
the modifiable factors involved in the autoimmune triad.”
Standard treatment for healing a leaky
gut involves dietary intervention and addressing SIBO, or small
intestinal bacterial overgrowth — which has been implicated as the
underlying cause of irritable bowel syndrome (IBS), Crohn’s disease,
Hashimoto’s hypothyroidism and celiac patients unresponsive to a
gluten-free diet.
Classified as a chronic infection of the
small intestine, SIBO causes the excessive fermentation of dietary
carbohydrates and results in flatulence, bloating, abdominal pain,
diarrhea and constipation. It’s also a major player in fostering a leaky
gut.
SIBO is normally treated with
antibiotics, although naturopaths have had success using high-potency
oregano oil. Avoiding FODMAP (fermentable oligo-, di-, mono-saccharides
and polyols) sugars, foods and refined carbohydrates may also be
necessary to combat the infection.
Dietitians also typically recommend an
elimination diet that restricts certain foods like wheat, gluten, soy,
dairy, eggs, nightshade vegetables, nuts and processed foods, which
contain proteins and other compounds that can contribute to autoimmune
flares and damage the gut.
But now health practitioners have yet another tool to help patients heal their leaky gut and calm autoimmune disorders: CBD oil
The Role of Cannabinoids in Alleviating Leaky Gut Syndrome
As we now know, cannabis has a wide-range of healing attributes
and has been used successfully for seizures, cancer, chronic pain and
much more. With leaky gut syndrome, researchers have found cannabinoids
act as an antioxidant, minimize intestinal permeability and also reduce
nausea, inflammation, as well as the associated pain response.
A 2011 study published in the British Journal of Pharmacology established that the phytocannabinoids THC and CBD reduced intestinal permeability in vitro.
The researchers believe cannabinoids increase a protein called
claudin-1, which creates tight junctions between intestinal cells and
reduces leaky gut syndrome.
The team concluded:
“These findings suggest that locally produced endocannabinoids, acting via CB1 receptors play a role in mediating changes in permeability with inflammation, and that phytocannabinoids have therapeutic potential for reversing the disordered intestinal permeability associated with inflammation.”
Moreover, cannabinoids suppress the
immune system — an important consideration since dysregulation of the
immune response is linked with LGS.
According to this study in the European Journal of Immunology:
“The cannabinoid receptor CB2 is found on the surface of many types of immune cells that cause inflammation. The use of CB2 agonists like THC can result in suppression of the immune system, which could help mitigate some of the autoimmune problems that are associated with LGS.”
Cannabinoids also reduce inflammation. Research
in Jerusalem, Israel found that non-psychotropic cannabidiol (CBD) oil
blocked the progression of arthritis and has great potential as a novel
anti-inflammatory agent.
The team also noted there is much
historical and cultural background in the use of cannabis. It was used
for the ‘poison of all limbs’ — presumably arthritis, according to
Ashurbanipal (died 625 BCE), dissolved edema and reduced inflammations
(Pedanius Dioscorides, died 199 CE), and was used in India as a poultice
over “inflamed, painful parts of the body.”
Overall, cannabis holds promise as a
powerful therapeutic agent in treating those with LGS and autoimmune
disease. More research is needed to fully understand the healing
mechanism behind cannabis and these disorders. However, if conventional
treatment isn’t providing relief, patients should discuss with their
healthcare provider the possibility of adding CBD oil into their
treatment plan.
Article sources:
About the author:
Carolanne Wright enthusiastically believes if we want to see change in the world, we need to be the
change. As a nutritionist, natural foods chef and wellness coach,
Carolanne has encouraged others to embrace a healthy lifestyle of
organic living, gratefulness and joyful orientation for over 13 years.
Through her website Thrive-Living.net,
she looks forward to connecting with other like-minded people from
around the world who share a similar vision. You can also follow
Carolanne on Facebook, Twitter and Pinterest.
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