This identifies an additional risk for heavy drinking and a
predisposition to cardiac arrhythmias that was not previously clear.
Of course heavy drinking has its own risks and needs to be guarded
against as if we have any hope of seeing that working.
There are benefits from having a glass of wine and that may even
apply to any other drink. The problem lies in developing the
personal discipline to stop there. Most likely that requires a
cultural change itself so that it is drunk strictly with a meal.
At least we now know that there is a link between the two and if you
suffer from any form of cardiac arrhythmia, then strictly managing
your use of alcohol is advised.
Alcohol May Trigger
Serious Palpitations in Heart Patients
ScienceDaily (June 1,
2012) — The term "holiday heart syndrome" was coined
in a 1978 study to describe patients with atrial fibrillation who
experienced a common and potentially dangerous form of heart
palpitation after excessive drinking, which can be common during the
winter holiday season. The symptoms usually went away when the
revelers stopped drinking. Now, research from UCSF builds on that
finding, establishing a stronger causal link between alcohol
consumption and serious palpitations in patients with atrial
fibrillation, the most common form of arrhythmia.
In a paper scheduled
to be published August 1 in the American Journal of Cardiology,
the UCSF researchers report that people with atrial fibrillation had
almost a four and a half times greater chance of having an episode if
they were consuming alcohol than if they were not.
"One of the
remaining big unknowns is why or how this happens," said senior
author Gregory Marcus, MD, assistant professor of medicine at the
UCSF Division of Cardiology. "In a previous publication, we
suggested that there was an effect on the electrical activity of the
atrium that leads to these arrhythmias but we do need additional
studies to prove that."
Alcohol and Heart
Palpitations
In the study,
conducted from September 2004 to March 2011, UCSF researchers
interviewed 223 patients with documented cardiac arrhythmia, a term
that encompasses both atrial fibrillation and supraventricular
tachycardia (SVT), or rapid heart rate originating above the
ventricles. Researchers asked patients, "Does alcohol trigger
your heart palpitations?" Participants ranked their symptoms on
a scale from one to five (i.e. never, rarely, sometimes, frequently,
and always).
"We defined 'yes'
as frequently or always versus the rest of the responses,"
Marcus said, "and found that, after adjusting for potential
confounders, atrial fibrillation patients had statistically
significant greater odds of reporting that alcohol would trigger
their symptoms." Of those patients interviewed, 133 reported
intermittent or paroxysmal atrial fibrillation, or irregular heart
palpitations, when drinking, and 90 had SVT, without any atrial
fibrillation. After adjusting for variables, the paroxysmal atrial
fibrillation group had a 4.42 greater chance of reporting alcohol
consumption as an arrhythmia trigger, compared to the SVT group.
Patients' claims of atrial fibrillation were verified by surface
electrocardiograms and invasive cardiac studies.
The mean age of the
study participants was 59 years. Eighty percent were Caucasian; 11
percent were Asian; 5 percent Latino, and 4 percent declined to state
their ethnicity in the atrial fibrillation group. All were referred
to and studied at UCSF.
"We didn't find
any clear associations between age and race as a trigger, but we
probably had insufficient number of people in the study," Marcus
said.
Studying the Effects
of Alcohol
Other studies have
suggested that alcohol could help decrease the chance of developing
atherosclerosis, which clogs or narrows the arteries. One of the
proposed sources of benefit is the antioxidant in red wine called
resveratrol, which may help prevent heart disease by increasing the
"good" cholesterol in a person's body.
"There may be
some beneficial effects to alcohol, but it's important to look at
actual heart outcomes, like stroke and death," Marcus said.
"Keep in mind that we used to think estrogen was good for your
heart based on observational studies, and now we know that's not
exactly true."
He says there's
insufficient information at this time to recommend any lifestyle
changes related to alcohol and heart disease risk. Still he points
out that this report and previous reports indicate alcohol can cause
cardiomyopathy and worsen hypertension.
"If someone has
heart palpitations or atrial fibrillation, I'm often asked, 'Can I
drink at all?'" Marcus said. "And I don't know the answer,
but it may be that certain people are susceptible.
"The clinical
evidence suggests that some people are susceptible and other people
aren't, but if they know that they're susceptible they should avoid
alcohol," he said.
Co-authors are Mala
Mandyam; Vasanth Vedantham, MD, PhD; Melvin Scheinman, MD; Zian
Tseng, MD, MAS; Nitish Badhwar, MBBS; Byron Lee, MD, MAS; Randall
Lee, MD, PhD; Edward Gerstenfeld, MD; and Jeffrey Olgin, MD, all of
the UCSF Division of Cardiology, Electrophysiology Section.
This study was
supported by the National Center for Research Resources, the National
Center for Advancing Translational Sciences, and the Office of the
Director, National Institutes of Health, through UCSF-CTSI Grant
Number TL1 RR024129. Its contents are solely the responsibility of
the authors and do not necessarily represent the official views of
the NIH.
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