Interestingly, psychiatrist Robert Hyde decided to conduct his
normal hospital rounds after ingesting the first American dose. He grew
irritated, believing to have received a bunk dose. Problem is, Hyde was
normally a pleasant man. He might not have achieved a schizophrenic
state (his dose was rather low), but the LSD certainly had an emotional
effect.
The government jumped aboard. The CIA's covert Project MKUltra was instituted in hopes of manipulating Russian spies to spill secrets. Officially sanctioned in 1953 (though trials began earlier), for two decades the US government secretly dosed a range of unsuspecting mental health patients, prostitutes, drug addicts, and prisoners in attempts of discovering LSD's abilities.
The government jumped aboard. The CIA's covert Project MKUltra was instituted in hopes of manipulating Russian spies to spill secrets. Officially sanctioned in 1953 (though trials began earlier), for two decades the US government secretly dosed a range of unsuspecting mental health patients, prostitutes, drug addicts, and prisoners in attempts of discovering LSD's abilities.
Sam Harris: Can psychedelics help you expand your mind?
Possession of LSD became illegal in 1968; the last sanctioned FDA
study on its effects took place 12 years later. Being categorized as a
Schedule 1 drug (no medical value), few researchers were willing to
touch it. But a recent uptick in studies have found that LSD is not
medically useless. It is being tested in treatment programs for
alcoholics and drug abusers. Microdosing has become a certified fad. And a recent study published in Nature found LSD might help you regulate your emotions.
Twenty
healthy participants with no or minimal (one time only) experience with
psychedelics ingested either 100μg LSD or a placebo. They were then
shown fearful or neutral faces while undergoing brain scans. Three brain
regions were focused on: the amygdala, the seat of emotional
processing, along with the fusiform gyrus and medial frontal gyrus, both
areas that are responsive to fearful faces.
The researchers'
hypothesis proved correct: LSD reduced amygdala activity. Those who took
the substance were less emotionally volatile in response to fearful
faces. To test against the possibility that the psychedelic effects
distorted faces, researchers cite a similar response
in subjects receiving 200μg LSD to fearful faces, who experienced no
alteration in the recognition of neutral, happy, or angry faces.
This
leads researchers to believe that LSD might help people suffering from
anxiety disorder and depression. By "reducing perception of negative
emotions and social cognitive deficits," LSD could soon find widespread
usage in the psychiatrist's arsenal of remedies. Of course dose and
mental history are important factors, but so far the results are
positive.
In 1956, psychedelic advocate Aldous Huxley wrote in his essay, Heaven and Hell:
The psychopharmacist cannot add to the faculties of the brain—but he can, at best, eliminate
obstructions and blockages which impede their proper use. He cannot
aggrandise us—but he can, within limits, normalise us; he cannot put
additional circuits into the brain, but he can, again within limits,
improve the co-ordination between existing ones, attenuate conflicts,
prevent the blowing of fuses, and ensure a steady power supply. That is
all the help we can ask for—but if we were able to obtain it, the
benefits to mankind would be incalculable.
Huxley was prescient in many ways. While Orwell's 1984 became a bestseller this year thanks to political turmoil in America, some have argued that Brave New World
is a better fit of our current predicament. Though brain scanners were
not available during Huxley's time he appears to have understood the
nuance of LSD's effects quite well. As research shows, LSD helps us
better coordinate our lives by helping us deal with our emotions in a
less fearful, more thoughtful manner.
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