The present reality regarding telomere therapies is one of surprising
outright success with zero side effects. All the reported cautions
are completely untested and speculative. It is rubbish until shown
otherwise by appropriate science.
Now we have a stunning age reversal in a nicely prepared animal
model. This powerfully indicates that we are way closer to outright
success than anyone ever imagined. This surely deserves a high five.
In the meantime individuals are out self testing the protocol at
serious expense and with little reporting underway. I would like to
see more and would welcome reports from users on my blog to assist
others.
I included a second item that introduces some current efforts toward
providing this technology without a pill.
Harvard scientists
reverse the ageing process in mice – now for humans
Harvard scientists were surprised that they saw a dramatic
reversal, not just a slowing down, of the ageing in mice. Now they
believe they might be able to regenerate human organs
Ian Sample, science
correspondent
Sunday 28 November
2010
Scientists claim to be
a step closer to reversing the ageing process after rejuvenating worn
out organs in elderly mice. The experimental treatment developed by
researchers at the Dana-Farber Cancer Institute, Harvard Medical
School, turned weak and feeble old mice into healthy animals by
regenerating their aged bodies.
The surprise recovery
of the animals has raised hopes among scientists that it may be
possible to achieve a similar feat in humans – or at least to slow
down the aging process.
An anti-ageing therapy
could have a dramatic impact on public health by reducing the burden
of age-related health problems, such as dementia, stroke and heart
disease, and prolonging the quality of life for an increasingly aged
population.
"What we saw in
these animals was not a slowing down or stabilisation of the
ageing process. We saw a dramatic reversal – and that was
unexpected," said Ronald DePinho, who led the study, which
was published in the journal Nature.
"This could lead
to strategies that enhance the regenerative potential of organs as
individuals age and so increase their quality of life. Whether it
serves to increase longevity is a question we are not yet in a
position to answer."
The ageing process is
poorly understood, but scientists know it is caused by many factors.
Highly reactive particles called free radicals are made naturally in
the body and cause damage to cells, while smoking, ultraviolet light
and other environmental factors contribute to ageing.
The Harvard group
focused on a process called telomere shortening. Most cells in the
body contain 23 pairs of chromosomes, which carry our DNA. At the
ends of each chromosome is a protective cap called a telomere. Each
time a cell divides, the telomeres are snipped shorter, until
eventually they stop working and the cell dies or goes into a
suspended state called "senescence". The process is behind
much of the wear and tear associated with ageing.
At Harvard, they bred
genetically manipulated mice that lacked an enzyme called telomerase
that stops telomeres getting shorter. Without the enzyme, the mice
aged prematurely and suffered ailments, including a poor sense of
smell, smaller brain size, infertility and damaged intestines and
spleens. But when DePinho gave the mice injections to reactivate the
enzyme, it repaired the damaged tissues and reversed the signs of
ageing.
"These were
severely aged animals, but after a month of treatment they showed a
substantial restoration, including the growth of new neurons in their
brains," said DePinho.
Repeating the trick in
humans will be more difficult. Mice make telomerase throughout their
lives, but the enzyme is switched off in adult humans, an
evolutionary compromise that stops cells growing out of control and
turning into cancer. [ Do we
really know this? - arclein ] Raising levels of telomerase
in people might slow the ageing process, but it makes the risk of
cancer soar.[ or does it? There
has been a lot of untested nonsense floating around this very new
line of inquiry. arclein]
DePinho said the
treatment might be safe in humans if it were given periodically and
only to younger people who do not have tiny clumps of cancer cells
already living, unnoticed, in their bodies.
David Kipling, who
studies ageing at Cardiff University, said: "The goal for human
tissue 'rejuvenation' would be to remove senescent cells, or else
compensate for the deleterious effects they have on tissues and
organs. Although this is a fascinating study, it must be remembered
that mice are not little men, particularly with regard to their
telomeres, and it remains unclear whether a similar telomerase
reactivation in adult humans would lead to the removal of senescent
cells."
Lynne Cox, a
biochemist at Oxford University, said the study was "extremely
important" and "provides proof of principle that short-term
treatment to restore telomerase in adults already showing age-related
tissue degeneration can rejuvenate aged tissues and restore
physiological function."
DePinho said none
of Harvard's mice developed cancer after the treatment. The team
is now investigating whether it extends the lifespan of mice or
enables them to live healthier lives into old age.
Tom Kirkwood, director
of the Institute for Ageing and Health at Newcastle University, said:
"The key question is what might this mean for human therapies
against age-related diseases? While there is some evidence that
telomere erosion contributes to age-associated human pathology, it is
surely not the only, or even dominant, cause, as it appears to be in
mice engineered to lack telomerase. Furthermore, there is the
ever-present anxiety that telomerase reactivation is a hallmark of
most human cancers."
Telomere Rejuvenation — Key To Health and Longevity
by
C. Norman Shealy, M.D., Ph.D.; Professor Emeritus of Energy Medicine,
Holos University Graduate Seminary
Abstract
Telomeres
ordinarily shrink by 1% annually, from birth to death. The telomeres
of people with unhealthy habits have much faster shrinkage, while
those of people with the best habits and genes shrink at a slower
rate, thus enabling such people to live to approximately 100 years.
Ultimately, telomere health is a major determinant of health and
longevity. Rejuvenation or regrowth of telomeres is, therefore, a
major key to longevity and health.
In
a pilot study, telomeres in 6 individuals, 3 men and 3 women from 50
to 74 years of age, were measured initially in lymphocytes and
neutrophils. Each participant then spent 30 minutes at least 5 days
each week sitting or lying in an electromagnetic field of 54 to 78
GHz, 50 to 75 decibels, or 1 billionth of a watt per centimeter
square.
These
same frequencies are reported to be present in ambient sunlight at an
intensity of ten-billionths of a watt per centimeter square. Human
DNA has been reported by Ukrainian physicists as resonating at 54 to
78 GHz.
After
3 months of this electromagnetically generated solar homeopathic
approach, average telomere length had increased 1%. After 10
months of use of the device, average telomere length had increased
2.9%. Theoretically this "reverses" 2.9 years of telomere
aging.
Using
this approach, a 75 year old would theoretically reverse telomere
aging by 50 years within a 14 year period. Obviously, many other
parameters of health need to be evaluated as we continue these
studies long term.
[
I find this to be an attractive protocol for both the apparent
efficacy but that it can obviously be also integrated into a
meditation discipline. - Arclein ]
Telomere Rejuventation
In
1925 a Russian engineer, Georges Lakhovsky, published his classic
book, The
Creation of Health,
in French. It was translated into English in 1935 and is still in
print. He stated that human DNA has a resonant frequency of 50+
gigahertz (GHz – billions of cycles per second).
In
the early 1980s, Ukrainian physicists determined that this frequency
was 54-78 GHz and further reported that a majority of illnesses were
"cured" by applying these frequencies to acupuncture
points. Lakhovsky further reported "curing" many illnesses,
including cancer, by applying a Tesla coil to two copper coils placed
three feet apart with patients sitting in the center of these coils
with the head near the center of the field induced by the Tesla coil.
Tesla coils emit a random range of frequencies from 1 Hz up to at
least 100 GHz.
In
1994, under an IRB protocol, 75 patients were treated with a
modification of the Lakhovsky apparatus.1 Twenty-five patients
each had rheumatoid arthritis, depression or chronic back pain. They
sat for 60 minutes daily, 5 days a week for 2 weeks, in a 24 inch
square cubicle, 48 inches high, with copper plates on the walls and a
copper tubing pyramid over the base so that the copper pyramid and
the copper base were physically connected. A Tesla coil was connected
to the copper tubing and activated during the treatment. At the end
of 2 weeks, 70% of the patients with depression or rheumatoid
arthritis were markedly improved but only half of the back patients
improved (Fig. 1).
Shortly
after that, a portable transcutaneous electrical nerve stimulator
(TENS) was developed. This device included output of 54-78 GHz at
50-75 decibels of energy, the same intensity used in the Ukraine.
Five specific acupuncture circuits were activated with this GigaTENS
device and specifically raised the DHEA, neurotensin, aldosterone or
calcitonin, while the 5th one lowered free radicals significantly.
All of these studies, except for aldosterone, have been
published.2,3,4 The circuit that raises DHEA was subsequently
proven to treat successfully 70 to 80% of patients with rheumatoid
arthritis, migraine, diabetic neuropathy, or depression. Stimulation
at these frequencies also increases calcitonin and lowers free
radicals.
Despite
the neurochemical and potential clinical benefits, most individuals
offered the opportunity to use these circuits would not spend the 30
minutes daily required for such treatment. Since the Ukrainians had
stated that these Giga frequencies are absorbed through the skin,
specifically through acupuncture points, it appeared that the only
reasonable way to immerse the body in these fields, without great
effort on the part of the individual, was to provide the field while
participants were lying down. Eventually this led to the creation of
a 2-inch thick polyfoam mat in the center of which is a copper screen
with crushed sapphire crystal placed over it. Copper wire from the
center of that mat leads to the Tesla coil. When the Tesla coil is
activated, a field of 54-78 GHz 2 feet high and around the mat is
produced. Six individuals volunteered to participate in the study.
Blood was drawn initially for analysis of telomere length of
granulocytes and lymphocytes.
Three
and one half months later, telomere length was measured again and in
4 of the 6 subjects, telomere length had increased by approximately
1%. At the end of 10 months, blood was again drawn and telomere
length had increased an average of 2.9%. Telomeres ordinarily shrink
1% every year from birth forward.
Telomeres
are responsible not only for the length of life but also the
integrity of DNA and thus ultimately for health itself. Individuals
using this approach can place the 2-inch mat on top of their
mattress, plug it into a timer that can go off in 30 to 60 minutes
while they are sleeping and obtain the benefit of "lying in a
field effect of human DNA." Continuing studies will be done. All
telomere blood tests were done at a reference lab, Repeat
Diagnostics.
References
1.
Shealy CN. Microwave resonance therapy: innovations from the
Ukraine. Greene
County Medical Bulletin 1993;
Vol. XLVII 3:15-17.
2.
Shealy CN, Myss CM. The ring of fire and DHEA: A theory for energetic
restoration of adrenal reserves. Subtle
Energies and Energy Medicine1995;6:167-175.
3.
Shealy CN, Borgmeyer V, Thomlinson P. Intuition, neurotensin and the
ring of air. Subtle
Energies and Energy Medicine 2002;11:145-150.
4.
Shealy CN, Borgmeyer V. Calcitonin enhancement with electrical
activation of a specific acupuncture circuit. AMERICAN
Journal of Pain Management 2003;13:29-32.
About the Author
- Norman Shealy, M.D., Ph.D. is President of Holos Institutes of Health, Inc., a non-profit organization focused on research, education and education in holistic health. He was the founding President of Holos University Graduate Seminary in Bolivar, Missouri, where he is now Professor Emeritus of Energy Medicine, and was founding President of the American Holistic Medical Association in 1978. He has 13 patents in the field of Energy Medicine, has published 26 books and 300 articles.
His
innovations include Dorsal Column Stimulation, Transcutaneous
Electrical Nerve Stimulation (TENS), Biogenics, the software for
self-regulation, and the RejuvaMatrix®, his most recent discovery,
for rejuvenating telomeres, the tips of DNA responsible for health
and longevity. His 14th patent is pending.
To
learn more, visit the Dr.
Norm Shealy web
site or contact him atnorm@normshealy.com.
See also Telomeres,
Health and Longevity.
Published
in Anti-Aging Therapeutics volume 12, by the American Academy of
Anti-Aging Medicine (A4M; www.worldhealth.net).
Reprinted with permission.
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