How Modern European Populations Have Evolved Over The Past 50,000 Years

The big change was the advent of agriculture and herding.  Let me exsplain why, because it happened in the USA over only a century.

A hunting bamd consists of at most perhaps twenty folks.  worse they are also in the habit of killing off neighboring men in other bands puting pressure on the male population.  Thus we preserve breeders and also suffer food shortages in the winter.  It is typically difficult for this global population to actually increaser.

with the advent of agriculture, the men no longer hunt much or raid their neighbors but concentrate in optimizing the land manged. Suddenly fathers are surviving and most of their children are3 surviving and the threat of starvation is hugely diminished.  

Better yet the population sustained is several times larger than nearby hunting bands.  Inter marriage soon drains surplus females from the bands and sooner or later they are drawn into their relatives lifeway.  I do think this natural process produced the dominant white pigmantation over the past two thousand years or quite recently.

How Modern European Populatiaons Have Evolved Over The Past 50,000 Years

gri

c4ulture and ultimately /06/2022 07:00:00 PM

https://archaeologynewsnetwork.blogspot.com/2022/04/how-modern-european-populations-have.html

After the Neolithic, European populations showed an increase in height and intelligence, reduced skin pigmentation and increased risk of cardiovascular disease due to genetic changes that lowered concentrations of 'good' HDL cholesterol. The changes reflect ongoing evolutionary processes in humans and highlight the impact the Neolithic revolution had on our lifestyle and health, write researchers from Nijmegen and Hannover in Frontiers in Genetics. Research of these past events offers interesting starting points for today's science and health care.

Credit: Radboud UMC

Just like plants, animals and other organisms, humans are dynamic organisms with variable traits. Look at how humans behave and their appearance and you will see differences in skin colour, eating habits, susceptibility to diseases, height and so on. Such external features are called 'phenotype'. This appearance (phenotype) can be influenced by, for example, genetic factors, social and cultural habits, eating behaviour and environmental factors.

Nijmegen scientists, in cooperation with colleagues from the Helmholtz Center for Infection Research (HZI, Hannover), have investigated whether they could trace the development of some complex human traits of modern Europeans from, say, 50,000 years B.C. to the present. These are complex traits such as height and intelligence. In this case, 'complex' means this trait is not determined by one gene but by dozens or even hundreds of genes. Each of these genes has only a very small effect on such a trait.

Genetic archaeology

How can you track down all the genes that interfere with height? This can be done with a technique called GWAS: genome-wide association studies. You take all human genes (genome) to see which genes have an effect on height. It's not a causal relationship (you do not know exactly how those genes influence height), but a statistical relationship (it is always the same genes that show up when height is determined).

In a large population study, you can get a list of genes involved in human height and compare this list of genes of modern Europeans with those of our distant ancestors. Archaeological research has unearthed already more than 800 people whose DNA has been mapped. Ultimately, this reference gives you a kind of timeline of European height genes, in which you can search for changes and turning points along the way.

Speeding up evolutionary processes

The researchers analyzed not only height but also other complex features such as skin pigmentation, weight/BMI, lipid metabolism, intelligence and cardiovascular disease. "In general, we see a clear change of some of these traits before and after the Neolithic Revolution, as if there was an acceleration of evolutionary processes then," says Mihai Netea from Radboudumc.

The Neolithic (New Stone Age) is an important period in human development, often referred to as the Neolithic Revolution. Wandering hunter-gatherers slowly disappeared and were replaced by locally settled farmers, resulting in a completely different lifestyle, change of diet, and different socio-cultural customs.

Height, skin colour, cholesterol

Yang Li, researcher at the HZI: "During this transitional period, we not only found a clear change in body height, but in skin colour as well. Europeans, for example, have retained their dark skin colour for a remarkably long time, and it really lightens during this period. This may be due to migration from populations in the Middle East with less pigmented skin. In many genes involved in metabolism and the risk of cardiovascular disease we saw little change, only with one obvious exception: HDL cholesterol -- often called 'good' cholesterol -- shows a clear decrease. It increases the risk of arthrosclerosis, but there's a link with intelligence as well."

Intelligence

There's a change in genetic factors that leads to the development of coronary artery disease by means of a decrease in HDL cholesterol. This raises the question, what is the evolutionary advantage of this lower HDL-cholesterol concentration.

"Perhaps it is in the development of cognitive functions, because cholesterol is fundamental to the development and functioning of the brain", says Li. "Some minimal changes in genes -- called polymorphisms -- in cholesterol metabolism have been linked to cognitive functions, while variations in levels of HDL and LDL have been linked to changes in intelligence, learning and memory. These are hypotheses, not proofs, but illustrate the importance of this research, in which we are exploring factors that can influence the development of complex human traits."

Useful for the present

This evolutionary research into the change of human traits in Europeans past can also be useful for the present. Netea: "It helps us to understand the physiology of contemporary humans and we may be able to tailor public health measures better to specific populations. Research has learned, for example, that Asian populations already have an increased risk of metabolic and cardiovascular complications at a lower BMI compared to European populations. We can take that into account in prevention strategies. Look at the mass rural-urban migration, which is accompanied by major changes in social and cultural habits, eating behaviour and environmental factors. What will it mean for important human physiological traits, for evolutionary pressures on human traits and genes, and human diseases in modern societies?"