The truth about Cannabidiol (CBD) and the cannabis plant in general can no longer be suppressed – and the exciting thing is that we are just at the beginning. We are literally just at the start on the long road of cannabis knowledge, which will take us to a deeper understanding of this astonishing plant, its varied uses and its manifold medical benefits. We still don’t even know how many cannabinoids (natural chemical compounds endemic to the cannabis plant) it contains – over the years the number has been revised in various places from 66 to 85 to 113+. We certainly don’t know the full range of effects of these cannabinoids, nor do we understand the synergistic way they work together, which is of the utmost importance. However, we do know enough to say that one of the foremost cannabinoids is cannabidiol or CBD, and we do know that it has incredible potential for healing a wide range of diseases, including diabetes, insomnia, anxiety, depression, migraines, asthma, scar tissue, Crohn’s, epilepsy, seizures, schizophrenia, Alzheimer’s, Parkinson’s and cancer.
“‘Relax, eat, sleep, forget and protect’ might be some of the messages that are produced by the actions of endocannabinoids, alone or in combination with other mediators …”
“Inflammation is a “hot” topic in medicine. It appears connected to almost every known chronic disease — from heart disease to cancer, diabetes to obesity, autism to dementia, and even depression. Other inflammatory diseases such as allergies, asthma, arthritis, and autoimmune disease are increasing at dramatic rates …”
“[cannabidiol decreases] the production and release of pro-inflammatory cytokines and decrease the activation of the LPS-induced STAT1 transcription factor, a key factor in some of the pro-inflammatory process. CBD, however, also reduces the activity of the NF-kappaB pathway, a primary pathway regulating pro-inflammatory genes, and upregulates the activation of the STAT3 transcription factor, which induces anti-inflammatory events (Kozela, et al., 2010).”