Thursday, September 4, 2014

Gold Therapy Hope for Brain Cancer

 A cancer cell containing nanoparticles of gold, which are coloured in green, and have entered the nucleus, which is the area in blue (University of Cambridge/PA)

MIT published the original work on this several years ago and i have been waiting ever since for it to be applied for the first time.  This is it.  It happens to be a real tool for surgically removing all cancer cells in the body.  It is pretty neat.

Most of what we see here is an exercise in advancing this therapy using the drug industries' resources without really letting on that this is an effective cure for cancer.

In fact I anticipate that this will be the safest protocol for eliminating cancer itself although there will be plenty to do to correct the victims environment a well.  We still wasted five years advancing this outright cure.

Gold therapy hope for brain cancer

There's a glimmer of hope to treating the most common form of brain cancer - in the form of gold dust.

Scientists from the University of Cambridge have found tiny particles of gold could be the key to treating glioblastoma multiforme - the most common and aggressive brain tumour in adults which is notoriously difficult to treat.

The treatment uses the "Trojan horse" method of smuggling nano-particles of gold into the brain to wipe out tumour cells.

Researchers engineered nanostructures containing gold and cisplatin - a conventional chemotherapy drug.

These were then released into tumour cells that had been taken from glioblastoma patients and grown in the lab.

Once inside, these "nanospheres" were exposed to radiotherapy.

This caused the gold to release electrons which damaged the cancer cells' DNA along with its overall structure, intensifying the impact of the chemotherapy drug in the process.

Apparently the technique was so effective that the cell culture showed no signs of regrowth even after 20 days, implying that the tumour cells had been destroyed.

"The combined therapy that we have devised appears to be incredibly effective in the live cell culture," says Mark Welland, professor of nanotechnology at Cambridge's St John's College.

"This is not a cure, but it does demonstrate what nanotechnology can achieve in fighting these aggressive cancers.

"By combining this strategy with cancer cell-targeting materials, we should be able to develop a therapy for glioblastoma and other challenging cancers in the future."

Glioblastoma has mostly proven to be very resistant to treatments - the reason being the tumour cells generally invade surrounding healthy brain tissue, which makes the surgical removal of the tumour virtually impossible.

Many sufferers die within a few months of diagnosis, with just six in every 100 patients with the condition managing to stay alive after five years.

Why are researchers are gunning for gold?

Scientists have been researching ways in which gold nanoparticles might be used in treatments.

Gold was chosen because it is a benign material which in itself poses no threat to the patient, and the size and shape of the particles can be controlled accurately.

When exposed to radiotherapy, the particles emit a type of low-energy electron, known as Auger electrons, capable of damaging the diseased cell's DNA.

This low-energy emission means that they only have an impact at short range, so they do not cause any serious damage to healthy cells that are nearby.

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