A chronic disease, ulcerative colitis is characterized by open sores or ulcers in the lining of the colon. The disease is estimated to affect 600,000 Americans, according to the Crohn’s & Colitis Foundation of
To gain a better understanding of how such therapy works, Dr. Loke and his colleagues analyzed a series of blood and tissue samples taken from a 34-year-old man living in California with ulcerative colitis who ingested Trichuris trichiura eggs (a roundworm that infects the lower intestine) after having researched the scientific literature. After several months, his condition improved dramatically and he remained in remission for almost three years. A subsequent cycle of self-treatment with the worm eggs achieved similar results.
“In essence, the worms trigger a big sneeze of the gut, which may have a beneficial side effect for ulcerative colitis,” says Dr. Loke, who does not advocate helminth therapy. “The problem is that these worms themselves can cause harm and damage the gut. The individual in this study is lucky to have responded so well, but for other people the worm infection may exacerbate bowel inflammation,” he says.